Thames Valley Police is appealing for information after a road traffic collision near Newbury.
At around 9.50pm on Saturday (11/6), a white Vauxhall Corsa was travelling southbound on the A34 just after the junction for Compton when it collided with the central reservation and crossed through the barrier, onto the opposite carriageway.
It was then in collision with a blue BMW 1 Series which was travelling northbound.
The driver of the Vauxhall Corsa, a 24-year-old man, sustained a broken leg, a ruptured aorta and other internal injuries.
The driver of the BMW, a 28-year-old man, sustained a serious head injury and spinal fracture.
Both were taken to the John Radcliffe Hospital for treatment and are currently still in hospital.
Police would like to speak to anyone who witnessed the collision or who has any other information which could help with the appeal.
If you have any information about the incident please contact investigating officer PC Jamie Payne from the Roads Policing Unit via the 24-hour Thames Valley Police enquiry line, 101, quoting reference number 1678 11/6.
If you do not want to speak directly to the police you can contact the independent charity Crimestoppers (opens new window) anonymously on 0800 555 111. No personal details are taken, information is not traced or recorded and you will not go to court.